Dr. Jack Ganley

About Dr. Jack Ganley

Dr. Jack is a Chembiochem : a European journal of chemical biology researcher from Duke University, Chemistry, Durham, UNITED STATES.. His recent research is on Coculturing of Mosquito-Microbiome Bacteria Promotes Heme Degradation in Elizabethkingia anophelis. which was published on Chembiochem on 2019/12/17.

The DOI of the article Coculturing of Mosquito-Microbiome Bacteria Promotes Heme Degradation in Elizabethkingia anophelis. is 10.1002/cbic.201900675

The article has been published in the following journal:
Germany Chembiochem 100937360 1439-4227

Co-Authors:


List of co-authors for Coculturing of Mosquito-Microbiome Bacteria Promotes Heme Degradation in Elizabethkingia anophelis. :
Hannah K D'Ambrosio
Meg Shieh
Emily Derbyshire

What are Dr. Jack Ganley Specialties :


Elizabethkingia HemS biliverdin heme degradation mosquito microbiome

List of Publications:

  1. Linking Genes to Molecules in Eukaryotic Sources: An Endeavor to Expand Our Biosynthetic Repertoire
      The discovery of natural products continues to interest chemists and biologists for their utility in medicine as well as facilitating our understanding of signaling, pathogenesis, and evolution. Despite an attenuation in the discovery rate of new molecules, the current genomics and transcriptomics r …
  2. Coculturing of Mosquito-Microbiome Bacteria Promotes Heme Degradation in Elizabethkingia Anophelis
      Anopheles mosquito microbiomes are intriguing ecological niches. Within the gut, microbes adapt to oxidative stress due to heme and iron after blood meals. Although metagenomic sequencing has illuminated spatial and temporal fluxes of microbiome populations, limited data exist on microbial growth dy …
  3. In Silico Screening and Evaluation of Plasmodium Falciparum Protein Kinase 5 (PK5) Inhibitors
      An in silico screen of 350 000 commercially available compounds was conducted with an unbiased approach to identify potential malaria inhibitors that bind to the Plasmodium falciparum protein kinase 5 (PfPK5) ATP-binding site. PfPK5 is a cyclin-dependent kinase-like protein with high sequence simila …
  4. Plasmodium Parasite Exploits Host aquaporin-3 During Liver Stage Malaria Infection
      Within the liver a single Plasmodium parasite transforms into thousands of blood-infective forms to cause malaria. Here, we use RNA-sequencing to identify host genes that are upregulated upon Plasmodium berghei infection of hepatocytes with the hypothesis that host pathways are hijacked to benefit p …
  5. Discovery of Antimicrobial Lipodepsipeptides Produced by a Serratia Sp. Within Mosquito Microbiomes
      The Anopheles mosquito that harbors the Plasmodium parasite contains a microbiota that can influence both the vector and the parasite. In recent years, insect-associated microbes have highlighted the untapped potential of exploiting interspecies interactions to discover bioactive compounds. In this …
  6. Exploring the Untapped Biosynthetic Potential of Apicomplexan Parasites
      Apicomplexan parasites encompass a diverse group of eukaryotic intracellular pathogens that infect various animal hosts to cause disease. Intriguingly, apicomplexans possess a unique organelle of algal origin, the apicoplast, which phylogenetically links these parasites to dinoflagellates and photos …
  7. Ethanolamine Catabolism in Pseudomonas Aeruginosa PAO1 Is Regulated by the Enhancer-Binding Protein EatR (PA4021) and the Alternative Sigma Factor RpoN
      The results of this study provide a basis for understanding ethanolamine catabolism and its regulation in Pseudomonas aeruginosa PAO1. Interestingly, expression of the ethanolamine-catabolic genes in this bacterium was found to be under the control of a positive-feedback regulatory loop in a manner …

Keywords :


Elizabethkingia HemS biliverdin heme degradation mosquito microbiome