Dr. Haruki Komatsu

About Dr. Haruki Komatsu

Dr. Haruki is a Hepatology research : the official journal of the Japan Society of Hepatology researcher from Department of Pediatrics, Toho University, Sakura Medical Center, Chiba, Japan.. His recent research is on Discordance of hepatitis B vaccination policies for healthcare workers between the United States, the United Kingdom and Germany. which was published on Hepatol Res on 2019/12/17.

The DOI of the article Discordance of hepatitis B vaccination policies for healthcare workers between the United States, the United Kingdom and Germany. is 10.1111/hepr.13470

The article has been published in the following journal:
Netherlands Hepatol Res 9711801 1386-6346

Co-Authors:


List of co-authors for Discordance of hepatitis B vaccination policies for healthcare workers between the United States, the United Kingdom and Germany. :
Paul Klenerman
Robert Thimme

What are Dr. Haruki Komatsu Specialties :


HBV DNA booster healthcare worker hepatitis B virus occult infection prophylaxis vaccine

List of Publications:

  1. Cytomegalovirus DNA in the Nails of an Infant Diagnosed With a Congenital Cytomegalovirus Infection
      Cytomegalovirus DNA in the Nails of an Infant Diagnosed With a Congenital Cytomegalovirus Infection
  2. Discordance of Hepatitis B Vaccination Policies for Healthcare Workers Between the USA, the UK, and Germany
      The hepatitis B (HB) vaccine is effective for the prevention of HB virus infection. It has been widely accepted that an anti-HB surface antibody (HBs) level ≥10 mIU/mL is protective against HB virus infection. Although transient infection can occur in individuals who attain a peak level of anti-HBs …
  3. Deep Sequencing of Hepatitis B Surface Antigen Gene in the Preserved Umbilical Cords in Immunoprophylaxis Failure Against Mother-To-Child HBV Transmission
      VEMs were present as minor populations in the preserved umbilical cords of children with breakthrough infections. The VEMs did not become major populations after the breakthrough infections. The evolution of VEMs from a minor form to a major form might not be a prerequisite for breakthrough infectio …
  4. Long-term Outcomes of Pediatric-Onset Primary Sclerosing Cholangitis: A Single-Center Experience in Japan
      The overall survival of pediatric-onset PSC in Japan was comparable to those in Western countries. The phenotype of PSC-autoimmune hepatitis was identified as a prognostic factor associated with a poorer long-term outcome.
  5. Liver Disease Secondary to Congenital Heart Disease in Children
      <span><b>Introduction</b>: Hepatic fibrosis and hepatocellular carcinoma (HCC) can develop in children with congenital heart disease. Although hepatic fibrosis and HCC are prone to develop after the Fontan operation, they can also develop in patients suffering from congenital heart disease who have not un</span> …
  6. Loss of Fibrocystin Promotes interleukin-8-dependent Proliferation and CTGF Production of Biliary Epithelium
      Congenital hepatic fibrosis (CHF) is a genetic liver disease caused by mutations of the PKHD1 gene. Dysfunction of the protein it encodes, fibrocystin, is closely associated with CHF pathogenesis. Using an in vitro human induced pluripotent stem cell model and patient samples, we showed that the los …
  7. Neonatal Meningoencephalitis Caused by Human Adenovirus Species F Infection
      Neonatal Meningoencephalitis Caused by Human Adenovirus Species F Infection
  8. Cholesterol Metabolism Is Enhanced in the Liver and Brain of Children With Citrin Deficiency
      HDL-C and sterol marker concentrations are elevated in citrin-deficient children post-NICCD. Moreover, cholesterol synthesis and elimination are markedly enhanced in the liver and brain of citrin-deficient children.
  9. Serum Amino Acid Profiling in Citrin-Deficient Children Exhibiting Normal Liver Function During the Apparently Healthy Period
      In the citrin-deficient children during the healthy stage, the characteristics of serum amino acids, including decrease of glucogenic amino acids, and increase of ketogenic amino acids, BCAAs, valine intermediate, and β-alanine, were found by comparison to the age-matched healthy control children, a …
  10. Treatment With Medium Chain Fatty Acids Milk of CD36-deficient Preschool Children
      Our results suggest that MCTs can prevent fasting hypoglycemia and exercise-induced myalgia in CD36-deficient young children.
  11. Usefulness of Serum Wisteria Floribunda Agglutinin-Positive Mac-2 Binding Protein in Children With Primary Sclerosing Cholangitis
      Serum WFA<sup>+</sup> -M2BP levels are useful to identify patients with advanced liver histology in pediatric PSC.
  12. Treatment With Granulocyte Colony-Stimulating Factor in the Refeeding Phase of Anorexia Nervosa Complicated With Severe Neutropenia and Sepsis: A Case Report
      Leukopenia is frequently observed in patients with anorexia nervosa (AN). However, serious infectious diseases are infrequent in patients with AN. We present the case of a 13-year-old girl with AN complicated with severe neutropenia and sepsis upon refeeding. Her body mass index was 11 kg/m<sup>2</sup> …
  13. Pediatric Hepatitis B Treatment
      Although the introduction of hepatitis B vaccine has been contributing to the reduction in the prevalence of hepatitis B virus (HBV) carriers worldwide, the treatment of children with chronic HBV infection is a challenge to be addressed. HBeAg seroconversion, which induces low replication of HBV, is …
  14. Acute Liver Dysfunction Not Resulting From Hepatitis Virus in Immunocompetent Children
      CMV, EBV, and HHV-6 DNA were frequently detected in immunocompetent children with acute liver dysfunction, but primary CMV and EBV infection were confirmed in 10-20% of the children with acute liver dysfunction. The combination of PCR assay and serology is necessary to make a diagnosis of acute live …
  15. Circulating Tricarboxylic Acid Cycle Metabolite Levels in Citrin-Deficient Children With Metabolic Adaptation, With and Without Sodium Pyruvate Treatment
      Citrin deficiency causes adult-onset type II citrullinemia (CTLN-2), which later manifests as severe liver steatosis and life-threatening encephalopathy. Long-standing energy deficit of the liver and brain may predispose ones to CTLN-2. Here, we compared the energy-driving tricarboxylic acid (TCA) c …
  16. Evaluation of the G145R Mutant of the Hepatitis B Virus as a Minor Strain in Mother-to-Child Transmission
      The role of the hepatitis B virus (HBV) mutant G145R, with a single change in amino acid 145 of the surface protein, as a minor population remains unknown in mother-to-child transmission. The minor strain as well as the major strain of the G145R mutant were evaluated in three cohorts using a locked …
  17. [IFN Therapy in Children With Chronic Hepatitis B]
      [IFN Therapy in Children With Chronic Hepatitis B]
  18. Chronic Hepatitis B in Children in the United States and Canada: International Origins Place the Disease Burden on Children Even in the Era of Universal Vaccination
      Chronic Hepatitis B in Children in the United States and Canada: International Origins Place the Disease Burden on Children Even in the Era of Universal Vaccination
  19. Two New Triterpenoids From the Seeds of Blackberry (Rubus Fructicosus)
      Two new ursane-type triterpenoids (1, 2) attached to isopropylidenedioxy group were isolated from the seeds of blackberry (Rubus fructicosus L., Rosaceae) along with two known ursane-type triterpenoids, 2,3-O-isopropylidenyl-2α,3α,19α-trihydroxyurs-12-en-28-oic acid (3) and 1β-hydroxyeuscaphic acid …
  20. Lack of Infectivity of HBV in Feces From Patients With Chronic Hepatitis B Virus Infection, and Infection Using Chimeric Mice
      Although the positive rate of fecal HBV DNA was high, the fecal HBsAg levels were extremely low. The chimeric mice were not infected with HBV after oral or intravenous inoculation with sterilized fecal samples. Therefore, feces from HBV carriers seem not to serve as an infectious vehicle for the tra …

Keywords :


HBV DNA booster healthcare worker hepatitis B virus occult infection prophylaxis vaccine