Dr. Courtney Kiggins

About Dr. Courtney Kiggins

Dr. Courtney is a Chembiochem : a European journal of chemical biology researcher from US Air Force Academy, Chemistry, 2355 Fairchild Dr, USAF Academy, 80840, UNITED STATES.. His recent research is on 8-oxo-7,8-dihydroguanosine inhibits or changes the selectivity of the theophylline aptamer. which was published on Chembiochem on 2019/12/17.

The DOI of the article 8-oxo-7,8-dihydroguanosine inhibits or changes the selectivity of the theophylline aptamer. is 10.1002/cbic.201900684

The article has been published in the following journal:
Germany Chembiochem 100937360 1439-4227

Co-Authors:


List of co-authors for 8-oxo-7,8-dihydroguanosine inhibits or changes the selectivity of the theophylline aptamer. :
Austin Skinner
Marino Resendiz

What are Dr. Courtney Kiggins Specialties :


aptamer design, 8-oxoG in aptamers, theophylline aptamer, aptamer selectivity, 8-oxoG

List of Publications:

  1. 7,8-Dihydro-8-oxoguanosine Lesions Inhibit the Theophylline Aptamer or Change Its Selectivity
      Aptamers are attractive constructs due to their high affinity/selectivity towards a target. Here 7,8-dihydro-8-oxoguanosine (8-oxoG) has been used, due in part to its unique H-bonding capabilities (Watson-Crick or Hoogsteen), to expand the "RNA alphabet". Its impact on the theophylline RNA aptamer w …
  2. Reactivity and Specificity of RNase T 1, RNase A, and RNase H Toward Oligonucleotides of RNA Containing 8-Oxo-7,8-dihydroguanosine
      Understanding how oxidatively damaged RNA interacts with ribonucleases is important because of its proposed role in the development and progression of disease. Thus, understanding structural aspects of RNA containing lesions generated under oxidative stress, as well as its interactions with other bi …

Keywords :


aptamer design, 8-oxoG in aptamers, theophylline aptamer, aptamer selectivity, 8-oxoG